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The Effect of Red Blood Cell Transfusion on Fatigue, Activity, and Fatigability in Hospitalized Patients with Anemia
February 13, 2019 @ 5:00 pm - 6:30 pm
FreeJoin the Graham School MSc in Biomedical Informatics program for this seminar.
The Effect of Red Blood Cell Transfusion on Fatigue, Activity, and Fatigability in Hospitalized Patients with Anemia
Micah Prochaska, MD, MS
Wednesday, February 13, 2018
5:00-6:30pm
Gleacher Center
Recent shifts in practice towards restrictive transfusion strategies in hospitalized patients with anemia have been made without clear and convincing evidence concerning the potential adverse effects on fatigue and functional outcomes. This is important because anemia increases the tendency to become fatigued at any given level of activity (fatigability), increasing fatigue and decreasing activity, which may ultimately impair functional outcomes. Given this, the goals of transfusion may include reducing fatigability, minimizing fatigue and increasing activity, which should be expected to improve functional outcomes. Thus, data on the effects of transfusion on fatigue, activity, and fatigability could inform the design of new transfusion strategies that may improve patient outcomes. One example is symptom-driven transfusion, in which patients would be transfused based on their symptoms, such as fatigue.
Speaker: Micah Prochaska, MD, MS, is an Assistant Professor of Medicine in the Department of Medicine at the University of Chicago. He is a hospitalist clinician and health outcomes researcher, and is currently supported by a grant from the National Heart, Lung, and Blood Institute (NHLBI) to study how red blood cell transfusion for hospitalized patients with anemia affects their fatigue, activity, and fatigability levels after they have been discharged from the hospital. Dr. Prochaska is also the Associate Director of the University of Chicago Hospitalist Project research infrastructure, and involved in the integration of the Chicago Area Patient Centered Outcomes Research Network (CAPriCORN) into clinical research at the University of Chicago. He is Director of the University of Chicago Translational Medicine Program (CTMP), and a Co-Director of the Cultivating Health & Aging Researchers by Integrating Science, Medicine, & Aging (CHARISMA) Program, both of which train undergraduate students in clinical and translational research. Dr. Prochaska is also a faculty member in the MacLean center for Clinical and Medical Ethics at the University of Chicago.
